Given are four pairs of amino acid sequences. Find out whether or not they are homologs. Test different algorithms for pairwise sequence comparisons. Do you find them by homology searches in the protein database, and if yes, under which conditions? Pair #1 Protein 1 (HrpB7 from Xanthomonas campestris pv. vesicatoria):
1 mrepaytwsv lhqlkarrce rmqerlsdcr ralehcdrel arcrqeaeac ttrlancdaa
61 lmdktgvggs ididtilqhe rfrtvlvetc raaeqaraaa dqslhsarde lasvqqalsk
121 lqaqaqvyad kaasarrarq aqrdaaeeed aiealvglrs hraahggar
Protein 2 (HrpD from Ralstonia solanacearum):
1 mkrkrrssvw ralieaktre rrrveadiea aqaalaeaqt avearqdalr qaeqrlddhl
61 rsmddlttgp sltaqaylqy dayrtqlegg vgqaeqavaa aqgvvaerea alqaqrrkla
121 rldamlercr etadrldrke daerelatee eaveailara ryttth
Pair #2
Protein 1 (HpaA from Xanthomonas campestris pv. vesicatoria):
1 mirrispgtl rpsvsiehgg shhhgdhhad asgtsagspt diaaraprlr papprrrrrg
61 irsldgqede fdaneqeeie akrecalrgr vsvaitpaqs rehgqgdqhg gdrsthtddp
121 qagpwhsaap aqlsdsirtc idaivdryvt rrdadpvakr halaaalvel ravgvshpav
181 apltatiwrl mrehlraydk ataaenllal rtrllelmps elepvpalrn fhlllplill
241 naekprrrvd rthaitrlnt llieqpqqaa qevrp
Protein 2 (HrpV from Ralstonia solanacearum):
1 mtritgpssa iytlpdpatt paqpaaatpn thrrrprqlh ereieheheq dhelqyqeql
61 tgrrkqlakl akrirrpglk rrnaanaade pttdsdfeel lmimeeharl skpllvgpsk
121 qgnphdgqqg rrgnnpqsdl agrhamlrry lleaeaaeaa kaeekasaqa ssapgkeags
181 aapvlpaqrk elaaqltgta eiptykmlla elcallyavr aghsmplrla lnlsrafika
241 splagapetl havkkdlvas vppaehkars ereeafhlll plmllsaslp rtstmksegy
301 arsgalarrw eaevwshqag vagmtvrpin vsa
Pair #3
Protein 1 (HrpD6 from Xanthomonas campestris pv. vesicatoria):
1 mrdhtmfdam tdavtqdmsk ilqakamdls gerlrnveta ldataqqirv hwsaasdqva
61 rndfnvlydg itaarnivah iasmp
Protein 2 (HrpX from Ralstonia solanacearum):
1 mfdrftpdii etfngvqafs kqdgakdfdp mrkaiaalre tsmefeqraf raantgdreq
61 lrtlaqgfga aadvcnglip s
Pair #4
Protein 1 (HrpE from Xanthomonas campestris pv. vesicatoria):
1 mqifpevssw rsrvgqgmdc ftgglsngis gaaalsgang qmdsllgdms asdeaqksmn
61 nkitmlkndl dfnvalnkfi gkagdnakql vgq
Protein 2 (HrpY from Ralstonia solanacearum):
1 magvpkpntt nttsttstfq sfangvddaa srtgfqaqyq aitaqgqqdm ldaakmqnal
61 nrtqmlaklm eagpkaakdl is
Latest update: October 15, 2009 Ralf Koebnik
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